Development, glycolytic activity, and viability of preimplantation mouse embryos subjected to different periods of glucose starvation.

@article{LeppensLuisier1997DevelopmentGA,
  title={Development, glycolytic activity, and viability of preimplantation mouse embryos subjected to different periods of glucose starvation.},
  author={G Leppens-Luisier and Denny Sakkas},
  journal={Biology of reproduction},
  year={1997},
  volume={56 3},
  pages={589-96}
}
After compaction, the preimplantation mouse embryo switches to a glucose-based metabolism, whereas for the 2- to 4-cell stage embryo, glucose can be inhibitory. In this study, we investigated the adaptability of preimplantation embryos to different periods of glucose starvation by culturing in vitro fertilized (IVF) and in vivo-fertilized 1-cell OF1 mouse embryos. Blastocysts obtained from exposure to glucose starvation for different periods of time were examined for the number of cells in the… CONTINUE READING