Development, characterization and clinical validation of new sensitive immunofluorometric assay for the measurement of serum thyroglobulin.

@article{Nakabashi2012DevelopmentCA,
  title={Development, characterization and clinical validation of new sensitive immunofluorometric assay for the measurement of serum thyroglobulin.},
  author={Cl{\'a}udia Cristina Doimo Nakabashi and Rosa Paula Mello Biscolla and Teresa Sayoko Kasamatsu and Teresinha T Tachibana and Rafaela N Barcelos and Eduardo Z Malouf and Danielle Macellaro Andreoni and Rui Monteiro de Barros Maciel and Jos{\'e} Gilberto Henriques Vieira},
  journal={Arquivos brasileiros de endocrinologia e metabologia},
  year={2012},
  volume={56 9},
  pages={658-65}
}
OBJECTIVE In the last decade, data published stressed the role of highly-sensitive thyroglobulin (Tg) assays in the follow-up of differentiated thyroid carcinoma (DTC) patients. The present study describes a new, highly-sensitive Tg assay, compares it with an available commercial assay, and validates it in the follow-up of DTC patients. SUBJECTS AND METHODS The immunofluorometric high-sensitivity Tg assay is based on monoclonal and polyclonal antibodies produced at our laboratories. It was… CONTINUE READING