Developing urinary metabolomic signatures as early bladder cancer diagnostic markers.

  title={Developing urinary metabolomic signatures as early bladder cancer diagnostic markers.},
  author={Chong Shen and Zeyu Sun and Deying Chen and Xiaoling Su and Jing Jiang and G Li and Biaoyang Lin and Jiajun Yan},
  journal={Omics : a journal of integrative biology},
  volume={19 1},
Early detection is vital to improve the overall survival rate of bladder cancer (BCa) patients, yet there is a lack of a reliable urine-based assay for early detection of BCa. Urine metabolites represented a potential rich source of biomarkers for BCa. This study aimed to develop a metabolomics approach for high coverage discovery and identification of metabolites in urine samples. Urine samples from 23 early stage BCa patients and 21 healthy volunteers with minimum sample preparations were… CONTINUE READING


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