Developing rat pineal cells manifest potential of neuronal differentiation in vitro.

@article{Araki1994DevelopingRP,
  title={Developing rat pineal cells manifest potential of neuronal differentiation in vitro.},
  author={Masasuke Araki and Takahiro Nonaka and Kimio Akagawa and Hiroto Kimura and Toshihiro Mashiko},
  journal={Neuroscience research},
  year={1994},
  volume={20 1},
  pages={57-69}
}
The pineal gland in mammals is an endocrine organ and generally does not exhibit neuronal characteristics. However, it is known that under culture conditions, cells from newborn rat pineals express properties characteristic of photoreceptors. Here, we studied the potential of rat pineal cells to differentiate into neuronal cell types using different neural markers. Three phenotype markers characteristic of nerve cells, i.e., intense GABA, neuron-specific antigen (HPC-1) and microtubule… CONTINUE READING