Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors.

  title={Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors.},
  author={Sharon M. Castellino and Nicole N J Ullrich and Megan J Whelen and Beverly J. Lange},
  journal={Journal of the National Cancer Institute},
  volume={106 8}
Survivors of childhood cancer frequently experience cancer-related cognitive dysfunction, commonly months to years after treatment for pediatric brain tumors, acute lymphoblastic leukemia (ALL), or tumors involving the head and neck. Risk factors for cancer-related cognitive dysfunction include young age at diagnosis, treatment with cranial irradiation, use of parenteral or intrathecal methotrexate, female sex, and pre-existing comorbidities. Limiting use and reducing doses and volume of… CONTINUE READING
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