Developing cell-free biology for industrial applications

@article{Swartz2006DevelopingCB,
  title={Developing cell-free biology for industrial applications},
  author={J. A. Swartz},
  journal={Journal of Industrial Microbiology and Biotechnology},
  year={2006},
  volume={33},
  pages={476-485}
}
  • J. Swartz
  • Published 9 May 2006
  • Biology, Chemistry, Medicine
  • Journal of Industrial Microbiology and Biotechnology
Although cell-free protein synthesis has been practiced for decades as a research tool, only recently have advances suggested its feasibility for commercial protein production. This focused review, based on the 2005 Amgen Award lecture, summarizes the relevant progress from the Swartz laboratory. When our program began, projected costs were much too high, proteins with disulfide bonds could not be folded effectively, and no economical scale-up technologies were available. By focusing on basic… Expand
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