Developing an alginate/chitosan hybrid fiber scaffold for annulus fibrosus cells.

@article{Shao2007DevelopingAA,
  title={Developing an alginate/chitosan hybrid fiber scaffold for annulus fibrosus cells.},
  author={Xinxin Shao and Christopher J Hunter},
  journal={Journal of biomedical materials research. Part A},
  year={2007},
  volume={82 3},
  pages={701-10}
}
A fibrous scaffold made of alginate or alginate/chitosan was fabricated for annulus fibrosus (AF) cell culture using a wet-spinning and lyophilization technique. The scaffolds were evaluated using several in vitro tests. Scanning electron microscopy showed the scaffold fibers generally aligned in one direction with individual fiber diameters varying between 40-100 microm. The alginate/chitosan hybrid scaffold exhibited a slower degradation rate, while both scaffold types did not display any… CONTINUE READING