Developing a set of ancestry-sensitive DNA markers reflecting continental origins of humans

@article{Kersbergen2009DevelopingAS,
  title={Developing a set of ancestry-sensitive DNA markers reflecting continental origins of humans},
  author={Paula Kersbergen and Kate van Duijn and Ate D. Kloosterman and Johan T den Dunnen and Manfred Kayser and Peter de Knijff},
  journal={BMC Genetics},
  year={2009},
  volume={10},
  pages={69 - 69}
}
The identification and use of Ancestry-Sensitive Markers (ASMs), i.e. genetic polymorphisms facilitating the genetic reconstruction of geographical origins of individuals, is far from straightforward. Here we describe the ascertainment and application of five different sets of 47 single nucleotide polymorphisms (SNPs) allowing the inference of major human groups of different continental origin. For this, we first used 74 cell lines, representing human males from six different geographical areas… CONTINUE READING