Developing a clinical decision model: MR spectroscopy to differentiate between recurrent tumor and radiation change in patients with new contrast-enhancing lesions.

@article{Smith2009DevelopingAC,
  title={Developing a clinical decision model: MR spectroscopy to differentiate between recurrent tumor and radiation change in patients with new contrast-enhancing lesions.},
  author={Ethan A. Smith and Ruth C. Carlos and Larry R Junck and Christina I. Tsien and Augusto R El{\'i}as and Pia C. Sundgren},
  journal={AJR. American journal of roentgenology},
  year={2009},
  volume={192 2},
  pages={W45-52}
}
OBJECTIVE Differentiation between recurrent neoplasm and postradiation change in patients previously treated for primary brain tumors is often difficult based on imaging features alone. The purpose of this study was to develop a method using alterations in the ratios of standard brain metabolites-choline (Cho), creatine (Cr), and N-acetylaspartate (NAA)-to predict the probability of tumor recurrence in patients previously treated for brain tumors with new contrast-enhancing lesions. MATERIALS… CONTINUE READING