Deuterium nuclear magnetic resonance unambiguously quantifies pore and collagen-bound water in cortical bone.

@article{Ong2012DeuteriumNM,
  title={Deuterium nuclear magnetic resonance unambiguously quantifies pore and collagen-bound water in cortical bone.},
  author={Henry H. Ong and Alexander C. Wright and Felix W. Wehrli},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2012},
  volume={27 12},
  pages={2573-81}
}
Bone water (BW) plays a pivotal role in nutrient transport and conferring bone with its viscoelastic mechanical properties. BW is partitioned between the pore spaces of the Haversian and lacuno-canalicular system, and water predominantly bound to the matrix proteins (essentially collagen). The general model of BW is that the former predominantly experiences fast isotropic molecular reorientation, whereas water in the bone matrix undergoes slower anisotropic rotational diffusion. Here, we… CONTINUE READING

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