Detrimental effects of standard medical therapy in congenital diaphragmatic hernia.

@article{Kays1999DetrimentalEO,
  title={Detrimental effects of standard medical therapy in congenital diaphragmatic hernia.},
  author={David William Kays and Max R Langham and Daniel J. Ledbetter and James Lewis Talbert},
  journal={Annals of surgery},
  year={1999},
  volume={230 3},
  pages={340-8; discussion 348-51}
}
OBJECTIVE To evaluate the impact of a nonstandard ventilation strategy on survival in congenital diaphragmatic hernia (CDH). BACKGROUND Despite recent advances, including nitric oxide, CDH remains an unsolved problem with a mortality rate of 35% to 50%. Hyperventilation and alkalization remain common therapies. METHODS In 1992, the authors prospectively… CONTINUE READING