Detrimental Effect of Hypercholesterolemia on High-Density Lipoprotein Particle Remodeling in Pigs.

@article{Padro2017DetrimentalEO,
  title={Detrimental Effect of Hypercholesterolemia on High-Density Lipoprotein Particle Remodeling in Pigs.},
  author={Teresa Padro and Judit Cubedo and Sandra Camino and Maria Teresa B{\'e}jar and Soumaya Ben-Aicha and Guiomar Mendieta and Joan Carles Escol{\`a}-Gil and Rafael Escate and Manuel Guti{\'e}rrez and Laura Casan{\'i} and Lina Badimon and Gemma Vilahur},
  journal={Journal of the American College of Cardiology},
  year={2017},
  volume={70 2},
  pages={
          165-178
        }
}
BACKGROUND Beneficial effects of high-density lipoproteins (HDL) seem altered in patients with symptomatic cardiovascular disease. We recently demonstrated in a swine model of ischemia-reperfusion (IR) that hypercholesterolemia abolishes HDL-related cardioprotection. OBJECTIVES This study sought to investigate, using the same animal model, whether the reported impairment of HDL cardioprotective function was associated with alterations in HDL remodeling and functionality. METHODS Pigs were… CONTINUE READING
32
Twitter Mentions

Citations

Publications citing this paper.
SHOWING 1-10 OF 12 CITATIONS

A Long Road Ahead for Discovering New HDL Metrics That Reflect Cardiovascular Disease Risk.

  • Journal of the American College of Cardiology
  • 2017
VIEW 11 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Altered HDL Remodeling and Functionality in Familial Hypercholesterolemia.

  • Journal of the American College of Cardiology
  • 2018
VIEW 3 EXCERPTS
CITES METHODS, RESULTS & BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 75 REFERENCES

HDL cholesterol efflux capacity and incident cardiovascular events.

  • The New England journal of medicine
  • 2014
VIEW 12 EXCERPTS
HIGHLY INFLUENTIAL

Unraveling the complexities of the HDL lipidome.

  • Journal of lipid research
  • 2013
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL