Deterministic characterization of phase noise in biomolecular oscillators.

@article{Koeppl2011DeterministicCO,
  title={Deterministic characterization of phase noise in biomolecular oscillators.},
  author={Heinz Koeppl and Marc Hafner and Ashok Ganguly and Abhi Mehrotra},
  journal={Physical biology},
  year={2011},
  volume={8 5},
  pages={055008}
}
On top of the many external perturbations, cellular oscillators also face intrinsic perturbations due the randomness of chemical kinetics. Biomolecular oscillators, distinct in their parameter sets or distinct in their architecture, show different resilience with respect to such intrinsic perturbations. Assessing this resilience can be done by ensemble stochastic simulations. These are computationally costly and do not permit further insights into the mechanistic cause of the observed… CONTINUE READING

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