Deterministic and Stochastic Regimes of Asexual Evolution on Rugged Fitness Landscapes

@article{Jain2007DeterministicAS,
  title={Deterministic and Stochastic Regimes of Asexual Evolution on Rugged Fitness Landscapes},
  author={Kavita Jain and Joachim H A Krug},
  journal={Genetics},
  year={2007},
  volume={175},
  pages={1275 - 1288}
}
We study the adaptation dynamics of an initially maladapted asexual population with genotypes represented by binary sequences of length L. The population evolves in a maximally rugged fitness landscape with a large number of local optima. We find that whether the evolutionary trajectory is deterministic or stochastic depends on the effective mutational distance deff up to which the population can spread in genotype space. For deff = L, the deterministic quasi-species theory operates while for… 

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