Determining the potency of neuromuscular blockers: are traditional methods flawed?

Abstract

BACKGROUND Traditionally, the clinical potency of neuromuscular blocking drugs has been measured using linear regression analysis (LRA) after log dose and probit or logit data transformation. However, probit and logit analyses are meant to handle only quantal responses with binomial error distributions, not continuous data such as per cent of maximal… (More)
DOI: 10.1093/bja/aeq094

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