Determining the optimal 5-FU therapeutic dosage in the treatment of colorectal cancer patients

Abstract

Fluorouracil (5-FU) has been wildly used as a primary medication in the treatment of solid tumors including colorectal cancer. The treatment efficacy and toxicity of 5-FU varies greatly among individuals, suggesting a need for individualized regimen for cancer patients. The present study analyzed the blood concentration of 5-FU and its therapeutic efficacy… (More)
DOI: 10.18632/oncotarget.11980

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