Determining the effect of ellagic acid on the proliferation and migration of pancreatic cancer cell lines

  title={Determining the effect of ellagic acid on the proliferation and migration of pancreatic cancer cell lines},
  author={Ji Yoon Kim and Yun Ju Choi and Ha-Jeong Kim},
  journal={Translational Cancer Research},
  pages={424 - 433}
Background Ellagic acid is a natural dietary compound found in several berries and fruits. It inhibits fibrosis, inflammation and carcinogenesis. We tried to find out what role ellagic acid plays in pancreatic cancer to see if it can be used as an adjuvant for chemotherapy. Methods Three pancreatic cancer cell lines, PANC-1, AsPC-1, and MIA PaCA-2, were used. Cell growth was measured by MTT assay. Activities of caspase-3 and caspase-8, and caspase-9 were evaluated to determine the apoptosis… 
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