Determining the cortical target of transcranial magnetic stimulation

@article{Thielscher2009DeterminingTC,
  title={Determining the cortical target of transcranial magnetic stimulation},
  author={Axel Thielscher and Felix A. Wichmann},
  journal={NeuroImage},
  year={2009},
  volume={47},
  pages={1319-1330}
}
Determining the cortical region that is effectively targeted by TMS to induce a reproducible behavioral effect is a non-trivial problem. In mapping experiments, a grid of coil positions is used to systematically assess the TMS effect on, e.g. muscle responses or error rates. The center-of-mass (CoM) of the response distribution is projected onto the cortex to determine the likely target site, implicitly assuming the existence of a single, contiguous target. The mapping results, however, often… CONTINUE READING

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