Determination of viridicatin in Penicillium cyclopium by capillary gas chromatography.

@article{Bringmann1997DeterminationOV,
  title={Determination of viridicatin in Penicillium cyclopium by capillary gas chromatography.},
  author={Gerhard Bringmann and Thilo Mader and Doris Feineis},
  journal={Analytical biochemistry},
  year={1997},
  volume={253 1},
  pages={
          18-25
        }
}
A sensitive gas chromatographic method for the determination of the quinoline alkaloid viridicatin, a fungal metabolite isolated from several Penicillium species and presumably a biogenetic precursor to naturally occurring diazepam-like 1,4-benzo-diazepines, has been developed. Prior to conversion of viridicatin into a volatile trimethylsilyl derivative, a rapid sample clean-up was accomplished by solid-phase extraction from mould mycelium on a C18 cartridge. Using synthetical 6-bromo… CONTINUE READING