Determination of trichloroethylene in biological samples by headspace solid-phase microextraction gas chromatography/mass spectrometry.

@article{Liu2008DeterminationOT,
  title={Determination of trichloroethylene in biological samples by headspace solid-phase microextraction gas chromatography/mass spectrometry.},
  author={Yongzhen Liu and Srinivasa Muralidhara and James V. Bruckner and Michael G Bartlett},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2008},
  volume={863 1},
  pages={26-35}
}
A simple, rapid and sensitive method for determination of trichloroethylene (TCE) in rat blood, liver, lung, kidney and brain, using headspace solid-phase microextraction (HS-SPME) and gas chromatography/mass spectrometry (GC/MS), is presented. A 100-microm polydimethylsiloxane (PDMS) fiber was selected for sampling. The major analytical parameters including extraction and desorption temperature, extraction and desorption time, salt addition, and sample preheating time were optimized for each… CONTINUE READING