Determination of the stereochemistry of hydride transfer from NADPH to FAD catalyzed by VlmR, a flavin reductase from the valanimycin biosynthetic pathway.

Abstract

[structure: see text]. The stereospecificity of hydride transfer from NADPH to FAD catalyzed by VlmR, a flavin reductase from the valanimycin biosynthetic pathway has been determined. By using stereospecifically deuterated NADPH, it has been shown that the 4-pro R hydrogen of NADPH is transferred.

Cite this paper

@article{Skae2001DeterminationOT, title={Determination of the stereochemistry of hydride transfer from NADPH to FAD catalyzed by VlmR, a flavin reductase from the valanimycin biosynthetic pathway.}, author={P N Skae and Ronald J Parry}, journal={Organic letters}, year={2001}, volume={3 8}, pages={1117-9} }