Determination of the specific interaction between palmatine and bovine serum albumin

@article{OuYang2011DeterminationOT,
  title={Determination of the specific interaction between palmatine and bovine serum albumin},
  author={Yu Ou-Yang and Xiao-Ling Li and Hong Yun Wang and Min Fang and Yan-Jun Hu},
  journal={Molecular Biology Reports},
  year={2011},
  volume={39},
  pages={5495-5501}
}
The binding of palmatine to bovine serum albumin (BSA) was studied under physiological conditions (pH = 7.40) by molecular spectroscopic approach. It was proved that the fluorescence quenching of BSA by palmatine is a result of the formation of palmatine–BSA complex. Binding parameters were determined using the modified Stern–Volmer equation and Scatchard equation, to measure the specific binding between palmatine and BSA. The thermodynamic parameters calculated, ∆G°, ∆H° and ∆S° indicate that… CONTINUE READING