Determination of the epigenetic effects of ochratoxin in a human kidney and a rat liver epithelial cell line.

@article{Horvath2002DeterminationOT,
  title={Determination of the epigenetic effects of ochratoxin in a human kidney and a rat liver epithelial cell line.},
  author={Anelia D. Horvath and Brad L. Upham and Varban Ganev and James Edward Trosko},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2002},
  volume={40 3},
  pages={273-82}
}
Epidemiological studies have implicated ochratoxin A (OTA), a fungal metabolic-contaminant of animal and human food sources, in Balkan Endemic Nephropathy and renal tumors. Many environmental toxicants operate through nongenotoxic mechanisms that epigenetically control gene expression leading to a diseased state. Gap junctional intercellular communication… CONTINUE READING