Determination of the enantiomeric composition of ibuprofen solutions via a rapid and sensitive mass spectrometry method

@inproceedings{Augusti2005DeterminationOT,
  title={Determination of the enantiomeric composition of ibuprofen solutions via a rapid and sensitive mass spectrometry method},
  author={Daniella Vasconcellos Augusti and Rodinei Augusti},
  year={2005}
}
Abstract A rapid and sensitive method for the determination of the enantiomeric composition of ibuprofen solutions is presented. This approach uses electrospray ionization tandem mass spectrometry and applies the kinetic method to perform the data analysis. Deviations of ca. 1.5% between the actual and experimental enantiomeric composition were observed. The simplicity, sensitivity, and precision of the method make it potentially suitable for the quantification of ibuprofen enantiomers in… CONTINUE READING

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