Determination of the cephalosporin antibiotic cephradine in human plasma by high-performance liquid chromatography with ultraviolet detection.

Abstract

A simple and sensitive high-performance liquid chromatographic method, for the determination of cephradine in human plasma samples has been developed and validated. Cephradine and cephaloridine (internal standard) were extracted from human plasma by perchloric acid protein precipitation followed by centrifugation. Aliquots of the extracts were analysed by… (More)

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@article{Johnson2000DeterminationOT, title={Determination of the cephalosporin antibiotic cephradine in human plasma by high-performance liquid chromatography with ultraviolet detection.}, author={Vanessa M. Johnson and Judith Allanson and Roger C Causon}, journal={Journal of chromatography. B, Biomedical sciences and applications}, year={2000}, volume={740 1}, pages={71-80} }