Determination of the activity of ponazuril against Sarcocystis neurona in cell cultures.

@article{Lindsay2000DeterminationOT,
  title={Determination of the activity of ponazuril against Sarcocystis neurona in cell cultures.},
  author={David S. Lindsay and Jitender Prakash Dubey and Thomas J Kennedy},
  journal={Veterinary parasitology},
  year={2000},
  volume={92 2},
  pages={165-9}
}
The present study examined the efficacy of ponazuril in inhibiting merozoite production of Sarcocystis neurona in cell cultures. Ponazuril inhibited merozoite production by more that 90% in cultures of S. neurona treated with 1.0 microg/ml ponazuril and greater than 95% inhibition of merozoite production was observed when infected cultures were treated with 5.0 microg/ml ponazuril. Ponazuril may have promise as a therapeutic agent in the treatment of S. neurona induced equine protozoal… CONTINUE READING

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