Determination of the Substrate Specificity of Protein Kinases with Peptide Micro- and Macroarrays.

Abstract

Elucidation of the key determinants for the phosphorylation site specificities of protein kinases facilitates identification of their physiological substrates, and serves to better define their critical roles in the signaling networks that underlie a multitude of cellular activities. Albeit with some apparent limitations, such as the lack of contextual… (More)
DOI: 10.1007/978-1-4939-3073-9_14

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