Determination of submicrogram-per-liter concentrations of caffeine in surface water and groundwater samples by solid-phase extraction and liquid chromatography.

@article{Burkhardt1999DeterminationOS,
  title={Determination of submicrogram-per-liter concentrations of caffeine in surface water and groundwater samples by solid-phase extraction and liquid chromatography.},
  author={Mark R Burkhardt and P P Soliven and Stephen L Werner and D G Vaught},
  journal={Journal of AOAC International},
  year={1999},
  volume={82 1},
  pages={161-6}
}
A method for determining submicrogram-per-liter concentrations of caffeine in surface water and groundwater samples has been developed. Caffeine is extracted from a 1 L water sample with a 0.5 g graphitized carbon-based solid-phase cartridge, eluted with methylene chloride-methanol (80 + 20, v/v), and analyzed by liquid chromatography with photodiode-array detection. The single-operator method detection limit for organic-free water samples was 0.02 microgram/L. Mean recoveries and relative… CONTINUE READING

Similar Papers

Loading similar papers…