Determination of steroid metabolome as a possible tool for laboratory diagnosis of schizophrenia.

@article{Bikov2013DeterminationOS,
  title={Determination of steroid metabolome as a possible tool for laboratory diagnosis of schizophrenia.},
  author={Marie Bi{\vc}{\'i}kov{\'a} and Martin Hill and Daniela Ř{\'i}pov{\'a} and Pavel Mohr and Richard Hampl},
  journal={The Journal of steroid biochemistry and molecular biology},
  year={2013},
  volume={133},
  pages={77-83}
}
Metabolomic studies represent a promising tool for early diagnosis of schizophrenia. The aim of this study was to find differences in the steroid spectrum in patients and controls, and to assess the diagnosis of schizophrenia by building a predictive model based on steroid data. Thirty-nine serum steroids (22 neuroactive steroids and their metabolites and 17 polar conjugates) representing steroid metabolome were measured by gas chromatography-mass spectrometry in 22 drug-naive (first episode… CONTINUE READING
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