Determination of single-nucleotide polymorphisms by real-time pyrophosphate DNA sequencing.

@article{Alderborn2000DeterminationOS,
  title={Determination of single-nucleotide polymorphisms by real-time pyrophosphate DNA sequencing.},
  author={Anders Alderborn and Ann Kristofferson and Ulrich Hammerling},
  journal={Genome research},
  year={2000},
  volume={10 8},
  pages={1249-58}
}
The characterization of naturally occurring variations in the human genome has evoked an immense interest during recent years. Variations known as biallelic Single-Nucleotide Polymorphisms (SNPs) have become increasingly popular markers in molecular genetics because of their wide application both in evolutionary relationship studies and in the identification of susceptibility to common diseases. We have addressed the issue of SNP genotype determination by investigating variations within the… CONTINUE READING

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Variations known as biallelic Single - Nucleotide Polymorphisms ( SNPs ) have become increasingly popular markers in molecular genetics because of their wide application both in evolutionary relationship studies and in the identification of susceptibility to common diseases .
Variations known as biallelic Single - Nucleotide Polymorphisms ( SNPs ) have become increasingly popular markers in molecular genetics because of their wide application both in evolutionary relationship studies and in the identification of susceptibility to common diseases .
Variations known as biallelic Single - Nucleotide Polymorphisms ( SNPs ) have become increasingly popular markers in molecular genetics because of their wide application both in evolutionary relationship studies and in the identification of susceptibility to common diseases .
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