Determination of silymarin flavonoids by HPLC and LC-MS and investigation of extraction rate of silymarin in Silybum marianum fruits by boiling water.

@inproceedings{Xiu2009DeterminationOS,
  title={Determination of silymarin flavonoids by HPLC and LC-MS and investigation of extraction rate of silymarin in Silybum marianum fruits by boiling water.},
  author={Weiming Xiu and Lan Rong Cai and Takeda Jun and Qin Qin Qiao and Tee Lee Hong and Zhen Lian and Shao and Kun Wang},
  year={2009}
}
A method has been developed for simultaneous separation and determination of seven important silymarin flavonoids by HPLC and LC-ESI/MS. The separation was completed on an ODS column using 1 % aqueous acetic acid solution and methanol as mobile phase with gradient elution. The methanol is better than acetonitrile as the organic modifier in mobile phase for separation of diastereomers of silybin (silybin A and silybin B) and diastereomers of isosilybin (isosilybin A and isosilybin B) was… CONTINUE READING

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SHOWING 1-2 OF 2 REFERENCES

Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects, AHRQ Evidence Reports, Numbers 1-60

  • AHRQ Evidence Reports, Summaries, 21. Milk Thistle
  • http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid…
  • 2006

Beijing, Vol

  • China Pharmaceutical University, Chinese Medicine Dictionary, Chinese Medical Science, Technology Publishing House
  • 1, p. 963
  • 1993

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