Determination of renal plasma flow by endogenous hippuric acid clearance in the conscious rat.

Abstract

(1) The endogenous hippuric acid can be fluorometrically determined down to a minimum of 0.6 micrograms/ml in 10 microliters of rat serum. This enables the determination of the effective renal plasma flow (ERPF) by measurement of the renal clearance of the endogenous hippuric acid in the conscious rat. (2) Endogenous hippuric acid clearance (128 ml/min . m2… (More)

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