Determination of reliable reference genes for multi-generational gene expression analysis on C. elegans exposed to abused drug nicotine

@article{Taki2013DeterminationOR,
  title={Determination of reliable reference genes for multi-generational gene expression analysis on C. elegans exposed to abused drug nicotine},
  author={Faten A. Taki and Baohong Zhang},
  journal={Psychopharmacology},
  year={2013},
  volume={230},
  pages={77-88}
}
More research has recently been focused on multigenerational toxicogenomics impacts. Such studies rely on behavioral as well as genetic and epigenetic analyses using various biotechniques. Of these technologies, quantitative reverse transcriptase PCR is considered as a mature discovery and validation tool. Nevertheless, the interpretation of the resulting gene expression necessitates the establishment of reliable internal controls for normalization. No study has been performed to identify… CONTINUE READING
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