Determination of progabide and its acid metabolite in biological fluids by high-performance liquid chromatography on silica column with ultraviolet detection.

Abstract

A high-performance liquid chromatographic method has been developed for the determination of progabide and its main acid metabolite in blood, serum and plasma. The assay involved a single and rapid extraction of drug and metabolite into toluene from the biological matrix buffered at pH 4.8, evaporation of the organic phase, and chromatography of the… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics