Determination of personalized diabetes treatment plans using a two-delay model.

  title={Determination of personalized diabetes treatment plans using a two-delay model.},
  author={S. M. Kissler and C. Cichowitz and S. Sankaranarayanan and D. Bortz},
  journal={Journal of theoretical biology},
  • S. M. Kissler, C. Cichowitz, +1 author D. Bortz
  • Published 2014
  • Medicine, Biology
  • Journal of theoretical biology
  • Diabetes cases worldwide have risen steadily over the past few decades, lending urgency to the search for more efficient, effective, and personalized ways to treat the disease. Current treatment strategies, however, may fail to maintain oscillations in blood glucose concentration that naturally occur multiple times per day, an important element of normal human physiology. Building upon recent successes in mathematical modeling of the human glucose-insulin system, we show that both food intake… CONTINUE READING
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