Determination of oxpentifylline and a metabolite, 1-(5'-hydroxyhexyl)-3,7-dimethylxanthine, by gas--liquid chromatography using a nitrogen-selective detector.

@article{Bryce1980DeterminationOO,
  title={Determination of oxpentifylline and a metabolite, 1-(5'-hydroxyhexyl)-3,7-dimethylxanthine, by gas--liquid chromatography using a nitrogen-selective detector.},
  author={T. A. Bryce and J. L. Burrows},
  journal={Journal of chromatography},
  year={1980},
  volume={181 3-4},
  pages={355-61}
}
A gas chromatographic method for the determination of oxpentifylline and a metabolite, 1-(5'-hydroxyhexyl)-3,7-dimethylxanthine is described. Oxpentifylline, metabolite and internal standard are extracted from basified plasma into dichloromethane, then the metabolite and internal standard are converted to their O-trifluoroacetates. Analysis by gas--liquid… CONTINUE READING