Determination of methadone in urine using ion trap GC/MS in positive ion chemical ionization mode.


Methadone is a potent analgesic and sedative. It is widely used in the treatment of heroin addiction and is often encountered in forensic specimens. In electron impact (EI) gas chromatography/mass spectrometry (GC/MS) mode, methadone produces predominantly a m/z 72 ion, which is not sufficiently characteristic for identification. Determination of the… (More)


  • Presentations referencing similar topics