Determination of lactic acid and poly(lactic acid)s in a dermatological formulation by capillary electrophoresis.


A stability-indicating capillary electrophoresis (CE) method was developed to determine lactic acid at a level of 0.9% m/m in a dermatological formulation. This level includes up to 34% present in the form of poly(lactic acid)s. Current methods which involve treatment of samples with sodium hydroxide to hydrolyse the various lactic acid oligomers to free… (More)


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