Determination of l-glutamic acid and γ-aminobutyric acid in mouse brain tissue utilizing GC-MS/MS.

@article{Farthing2017DeterminationOL,
  title={Determination of l-glutamic acid and γ-aminobutyric acid in mouse brain tissue utilizing GC-MS/MS.},
  author={Christine A Farthing and Don E. Farthing and Ronald E Gress and Douglas H. Sweet},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2017},
  volume={1068-1069},
  pages={64-70}
}
A rapid and selective method for the quantitation of neurotransmitters, l-Glutamic acid (GA) and γ-Aminobutyric acid (GABA), was developed and validated using gas chromatography-tandem mass spectrometry (GC-MS/MS). The novel method utilized a rapid online hot GC inlet gas phase sample derivatization and fast GC low thermal mass technology. The method… CONTINUE READING