Determination of irritant threshold concentrations to weeds, trees and grasses through serial dilutions in intradermal testing on healthy clinically nonallergic dogs.

@article{Bauer2010DeterminationOI,
  title={Determination of irritant threshold concentrations to weeds, trees and grasses through serial dilutions in intradermal testing on healthy clinically nonallergic dogs.},
  author={Cynthia L Bauer and Patrick Hensel and Michaela G. Austel and Deborah Keys},
  journal={Veterinary dermatology},
  year={2010},
  volume={21 2},
  pages={192-7}
}
Irritant threshold concentration (ITC) for intradermal testing (IDT) was determined in 31 healthy, clinically nonallergic dogs. Twenty-three allergens were tested at five variable concentrations ranging from 1000 to 8000 PNU/mL. To distinguish irritant reactions from subclinical IgE-mediated hypersensitivities, serum allergy testing was performed. ITCs were determined by evaluating the lowest concentration to which no dogs (0% cut-off) and to which at least 10% of dogs (> or = 10% cut-off… CONTINUE READING