Determination of intracellular cytokines produced by Th1 and Th2 cells using flow cytometry in patients with brucellosis.

@article{Akbulut2005DeterminationOI,
  title={Determination of intracellular cytokines produced by Th1 and Th2 cells using flow cytometry in patients with brucellosis.},
  author={H. Handan Akbulut and S{\"u}leyman Sirri Kiliç and Vedat Bulut and Mehmet Ozden},
  journal={FEMS immunology and medical microbiology},
  year={2005},
  volume={45 2},
  pages={
          253-8
        }
}
The aim of the study was to evaluate intracellular interferon-gamma (IFN-gamma), and interleukin-4 (IL-4) levels in pre- and post-treatment periods of brucellosis patients and to determine the relationship between these parameters and patients' clinical findings. Twenty-five patients diagnosed as brucellosis and 11 aged-matched healthy volunteers were included in the study. CD3+CD4+ T lymphocytes levels were significantly lower in patients with brucellosis as compared to the control group. CD3… CONTINUE READING

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