Determination of in vivo carbon monoxide production in laboratory animals via exhaled air.

@article{Dercho2006DeterminationOI,
  title={Determination of in vivo carbon monoxide production in laboratory animals via exhaled air.},
  author={Ryan A. Dercho and Kanji Nakatsu and Ronald J Wong and David K. Stevenson and H. Vreman},
  journal={Journal of pharmacological and toxicological methods},
  year={2006},
  volume={54 3},
  pages={288-95}
}
INTRODUCTION In vitro assays play an important role in the understanding of the heme oxygenase (HO)/carbon monoxide (CO) pathway. However, because physiological roles for the products of this pathway are hypothesized, it is becoming increasingly important to perform in vivo studies. Since CO production is primarily mediated by HO and is excreted mainly by… CONTINUE READING