Determination of hemisphere dominance for language: comparison of frontal and temporal fMRI activation with intracarotid amytal testing

@article{Spreer2002DeterminationOH,
  title={Determination of hemisphere dominance for language: comparison of frontal and temporal fMRI activation with intracarotid amytal testing},
  author={Joachim Spreer and Susanne L Arnold and Ansgar Quiske and Robert Wohlfarth and Sargon Ziyeh and Dirk-Matthias Altenm{\"u}ller and Martin Herpers and Jan Kassubek and Joachim Klisch and B J Steinhoff and J{\"u}rgen Honegger and Andreas Schulze-Bonhage and M Schumacher},
  journal={Neuroradiology},
  year={2002},
  volume={44},
  pages={467-474}
}
The reliability of frontal and temporal fMRI activations for the determination of hemisphere language dominance was evaluated in comparison with intracarotid amytal testing (IAT). Twenty-two patients were studied by IAT (bilateral in 13, unilateral in 9 patients) and fMRI using a paradigm requiring semantic decisions. Global and regional (frontal and temporoparietal) lateralisation indices (LI) were calculated from the number of activated (r>0.4) voxels in both hemispheres. Frontolateral… CONTINUE READING