Determination of gentamicin in pharmaceutical formulations using peroxyoxalate chemiluminescent detection in flow-injection analysis.

@article{FernndezRamos2006DeterminationOG,
  title={Determination of gentamicin in pharmaceutical formulations using peroxyoxalate chemiluminescent detection in flow-injection analysis.},
  author={Jos{\'e} M Fern{\'a}ndez-Ramos and Ana M Garc{\'i}a-Campa{\~n}a and Ferm{\'i}n Al{\'e}s-Barrero and Juan Manuel Bosque-Sendra},
  journal={Talanta},
  year={2006},
  volume={69 3},
  pages={763-8}
}
A simple and sensitive procedure for the determination of gentamicin is presented, based on the use of the peroxyoxalate chemiluminescent (PO-CL) system in presence of imidazole as a catalyst. The gentamicin has to be previously derivatized with o-phthaladehyde (OPA) in order to obtain a fluorophore, which participates in the PO reaction, producing a CL… CONTINUE READING