Determination of gastric emptying in nonobese diabetic mice.

@article{Choi2007DeterminationOG,
  title={Determination of gastric emptying in nonobese diabetic mice.},
  author={K. M. Choi and J. Zhu and G. Stoltz and S. Vernino and M. Camilleri and J. Szurszewski and S. Gibbons and G. Farrugia},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2007},
  volume={293 5},
  pages={
          G1039-45
        }
}
Animal studies on diabetic gastroparesis are limited by inability to follow gastric emptying changes in the same mouse. The study aim was to validate a nonlethal gastric emptying method in nonobese diabetic (NOD) LtJ mice, a model of type 1 diabetes, and study sequential changes with age and early diabetic status. The reliability and responsiveness of a [(13)C]octanoic acid breath test in NOD LtJ mice was tested, and the test was used to measure solid gastric emptying in NOD LtJ mice and… Expand
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