Determination of fructose 2,6-bisphosphate in human lymphocytes is a potential laboratory test in diabetology

Abstract

The conventional micromethod of fructose 2,6-bisphosphate (F-2,6-P2) determination is optimized for human peripheral blood lymphocytes. The F-2,6-P2 content in lymphocytes of healthy subjects is 0.8±0.2 pmol/106 cells or 6.7±1.1 pmol/mg protein. Preliminary findings show a decrease in the F-2,6-P2 content in lymphocytes from patients with severe diabetes mellitus.

DOI: 10.1007/BF02446591

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Cite this paper

@article{Belyaeva2006DeterminationOF, title={Determination of fructose 2,6-bisphosphate in human lymphocytes is a potential laboratory test in diabetology}, author={N. F. Belyaeva and M . A . Golubev and Marina S Markova and O. L. Kol'chenko and N. N. Lamzina and V. K. Gorodetskii and L. N. Viktorova and Mikhail I. Balabolkin and B. F. Korovkin}, journal={Bulletin of Experimental Biology and Medicine}, year={2006}, volume={122}, pages={950-952} }