Determination of endogenous ethanol in blood and breath by gas chromatography-mass spectrometry

@article{Jones1983DeterminationOE,
  title={Determination of endogenous ethanol in blood and breath by gas chromatography-mass spectrometry},
  author={A. Jones and G. M{\aa}rdh and E. {\"A}ngg{\aa}rd},
  journal={Pharmacology Biochemistry and Behavior},
  year={1983},
  volume={18},
  pages={267-272}
}
We describe methods for the determination of endogenous ethanol in biological specimens from healthy abstaining subjects. The analytical methods were headspace gas chromatography (GC) for plasma samples and gas chromatography-mass spectometry (GC/MS) with deuterium labelled species 2H3-ethanol and 2H5-ethanol as internal standards for breath analysis. Ethanol in rebreathed air was about 10% higher than in directly analysed end-expired alveolar air. Known volumes of rebreathed air were passed… Expand
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