Corpus ID: 3898056

Determination of elemental composition and median lethal dose of calabash chalk

@inproceedings{Ekong2015DeterminationOE,
  title={Determination of elemental composition and median lethal dose of calabash chalk},
  author={Moses B. Ekong and Aniekan Imo Peter and Theresa Bassey Ekanem and Eme Efiom Osim},
  year={2015}
}
Calabash chalk is a geophagic material consumed mostly for its emetic function, though other reasons are not rule out. A report of a sample analysis revealed toxic metals/metalloids, as well as persistent organic pollutants. This lead to this study to investigate the elemental composition of a sample from southern Nigeria, and to determine its median lethal dose. Nonsalted calabash chalk was analyzed for the presence of some major and trace elements using inductively coupled plasma-mass… Expand

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References

SHOWING 1-10 OF 51 REFERENCES
Characterisation and analysis of persistent organic pollutants and major, minor and trace elements in Calabash chalk.
TLDR
A range of persistent organic pollutants were identified and quantified in Calabash chalk including alpha lindane, endrin, endosulphan II and p,p'-DDD using PFE-GC-MSD. Expand
Human Geophagia, Calabash Chalk and Undongo: Mineral Element Nutritional Implications
TLDR
Investigations indicate that at the reported rates of ingestion, Calabash chalk on the whole is not an important source of mineral nutrients or PHEs to humans, and although Undongo contains elevated pseudo-total concentrations of chromium and nickel, this soil is not a significant source to humans for any of the bioaccessible elements investigated. Expand
Trace Element Concentrations of Three Soils in Central Appalachia
Background concentrations of trace elements in soils are important due to recent interest in contamination potential and toxic effect of these elements on humans and the environment.. We assessed theExpand
The effect of calabash chalk on some hematological parameters in female adult Wistar rats.
TLDR
It is inferred that calabash chalk, particularly the non-salted form, alters the normal concentration of Hb, RBC and Pl counts, and ESR, as observed in the female Wistar rats studied. Expand
Calabash Chalk's Geophagy Affects Gestating Rats' Behavior and the Histomorphology of the Cerebral Cortex
TLDR
There was no difference in ambulatory activities, but group 4 animals had more () transition frequency and were more averse to the dark in the light and dark field, while sections of the cerebral cortex showed a higher () cellular population, hypertrophied pyramidal cells, and vacuolations in the treatment groups. Expand
Iron nutrition and possible lead toxicity: An appraisal of geophagy undertaken by pregnant women of UK Asian communities
Abrahams, Peter, (2006) 'Iron nutrition and possible lead toxicity: an appraisal of geophagy undertaken by pregnant women of UK Asian communities', Applied Gechemistry 21 pp.98-108 RAE2008
Effect of calabash chalk on the histomorphology of the gastro-oesophageal tract of growing wistar rats.
TLDR
Calabash chalk caused histological changes to the stomach and the oesophagus that may lead to other pathophysiological conditions, including oedema with haemorrhages in the mucosa of the stomach, and acanthosis, hyperkeratosis, and koilocytic changes were observed in the membranes of the oeosophagus of the groups treated with 40 mg/mL of CalabASH chalk suspension. Expand
Effect of calabash chalk on the histomorphology of the gastro-oesophageal tract of growing wistar rats.
TLDR
There was oedema with haemorrhages in the mucosa of the stomach, and acanthosis, hyperkeratosis, and koilocytic changes were observed in the membranes of the oesophagus of the groups treated with 40 mg/mL of Calabash chalk suspension. Expand
Differentia Effects Of Calabash Chalk On The Histology Of The Liver Of Adult Wister Rats
TLDR
It is inferred that the non-salted calabash chalk is detrimental to health unlike the salted calABash chalk, which is prone to susceptibility to other form of toxins. Expand
Reproductive ability of workmen occupationally exposed to lead.
TLDR
Lead poisoning as well as moderate increased absorption of lead decrease the fertile ability of men and Hypofertility induced by lead is due, perhaps, to its direct toxic effect on the gonads, as no interference with the hypothalamopituitary axis were evidenced. Expand
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