Determination of diosmin in pharmaceutical formulations using Fourier transform infrared spectrophotometry.

@article{Bunaciu2009DeterminationOD,
  title={Determination of diosmin in pharmaceutical formulations using Fourier transform infrared spectrophotometry.},
  author={Andrei A. Bunaciu and Gabriela Elena Udriştioiu and Lavinia Liliana Ruta and Serban Fleschin and Hassan Y Aboul-Enein},
  journal={Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society},
  year={2009},
  volume={17 4},
  pages={303-6}
}
A Fourier transform infrared (FT-IR) spectrometric method was developed for the rapid, direct measurement of diosmin in different pharmaceutical drugs. Conventional KBr-spectra were compared for best determination of active substance in commercial preparations. The Beer-Lambert law and two chemometric approaches, partial least squares (PLS) and principal component regression (PCR+) methods, were tried in data processing. 

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