Determination of common parameters fo iodothyronine metabolism and distribution in man by noncompartmental analysis.

@article{Oppenheimer1975DeterminationOC,
  title={Determination of common parameters fo iodothyronine metabolism and distribution in man by noncompartmental analysis.},
  author={Jack H. Oppenheimer and Heather L Schwartz and Martin I. Surks},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1975},
  volume={41 2},
  pages={319-24}
}
A noncompartmental method is proposed for the calculation of the total distribution volume of exchangeable iodothyronine, the fractional irreversible removal rate from the exchangeable pool, and the metabolic clearance rate of labeled triiodothyronine (T3) and thyroxine (T4). The method depends on a graphic analysis and does not require the use of computers. The results of noncompartmental analysis of T3 and T4 distribution and metabolism are compared to single compartmental calculations in 12… CONTINUE READING

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